enveloped DNA

Thermal Stabilization of Viral Vaccines in Low-Cost Sugar Films

Vincent Leung, Jonathan Mapletoft, Ali Zhang, Amanda Lee, Fatemeh Vahedi, Marianne Chew, Alexandra Szewczyk, Sana Jahanshahi-Anbuhi, Jann Ang, Braeden Cowbrough, Matthew S. Miller, Ali Ashkar & Carlos D. M. Filipe

Most currently available vaccines, particularly live vaccines, require the cold chain, as vaccine efficacy can be significantly hampered if they are not stored in a temperature range of 2–8 °C at all times. This necessity places a tremendous financial and logistical burden on vaccination programs, particularly in the developing world. The development of thermally stable vaccines can greatly alleviate this problem and, in turn, increase vaccine accessibility worldwide. In …

Sci. Rep. 2019;9:7631.
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